Endocrine Abstracts

Recurrent hyperparathyroidism (HPT) refers to reappearance of hypercalcemia after a normocalcemic period of at least 6 months post-parathyroidectomy. Parathyroid carcinoma is a rare cause of primary hyperparathyroidism (pHPT), accounting for 0.4–5.2% of cases. Parathyromatosis is defined as small nodules of hyperfunctioning parathyroid tissue scattered in the soft tissues of the neck and/or mediastinum. We describe two cases with recurrent hypercalcemia after surgical int...

Introduction: Differentiated thyroid cancer is one of the most common endocrine malignancies. The most common thyroid cancer in adolescence is PTC. It presents with a high rate of loco regional ganglionic metastasis. Hodgkin lymphoma (HL) is a heterogeneous group of neoplasms with an incidence, in Europe, estimated around 2.2–2.7 per 100 000 cases per year. In front of each adolescent case, with concomitant thyroid and lymph nodes, the main question that arises is the pre...

Background: Acromegaly is a chronic rare disease induced by persistent hypersecretion of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) in adult patients. Several studies have associated acromegaly with an increased risk for developing different benign or malignant tumors.Case presentation: A 33-year old female patient was diagnosed with acromegaly due to a large pituitary macroadenoma, in 2009. In the same period, she was also diagnosed wi...

Aim: To show the etiology of thyromegaly in our region to asses the rationale treatment and follow up.Material and methods: Between 2005 and 2010, we have studied the prevalence and etiologic profile of the children with thyromegaly admitted in the Endocrinology Department of our hospital. The working protocol included: weight and length birth, gestational age, auxological parameters and pubertal stages after Tanner’s criteria, morphogram, laborator...

IntroductionThe use of antithyroid drugs is associated rarely with severe hepatotoxicity. Recently, due to several cases reported in the literature, acute pancreatitis was added as a severe potential adverse effect induced by methimazole. The physiopathology of methimazole induced pancreatitis is not fully understood (intrinsic toxicity or idiosyncratic drug reaction were proposed as possible mechanisms). If adverse effects occur and no other treatment o...